Scientific Research & Evidence

Vitamin E

1. “How vitamin E can help prevent cancer”, Ohio State University. ScienceDaily, 14 March 2013.
   https://www.sciencedaily.com/releases/2013/03/130314175659.htm
2. “Vitamin E supplements might lower the risk of advanced prostate cancer in smokers”, Harvard School of Public Health, 2019
   https://www.hsph.harvard.edu/nutritionsource/vitamin-e/

Vitamin B-6

1. “Vitamin B6 tied to better prostate cancer survival”, American Journal of Clinical Nutrition, September 2009.
   https://www.reuters.com/article/us-vitamin-b6/vitamin-b6-tied-to-better-prostate-cancer-survival-idUSTRE58L3MD20090922
2. “Epidemiological evidence supports the potential of vitamin B6 as a cancer risk reduction agent”, JNCI: Journal of the National Cancer Institute, Volume 109, Issue 3, March 2017, djw230
   https://academic.oup.com/jnci/article/109/3/djw230/2572054

Zinc

1. A comprehensive review of the role of zinc in normal prostate function and metabolism; and its implications in prostate cancer.
   https://www.ncbi.nlm.nih.gov/pubmed/27132038
2. “Zinc as an anti-tumor agent in prostate cancer and in other cancers.” Franklin RB, Costello LC. Arch Biochem Biophys. 2007 Jul 15;463(2):211-7.
   https://www.ncbi.nlm.nih.gov/pubmed/17400177

Copper

1. “Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution” Oncotarget. 2016 Jun 14; 7(24): 37064–37080. Published online 2016 May 9. doi: 10.18632/oncotarget.9245
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095059/

Selenium

1. “Selenium May Cut Aggressive Prostate Cancer Risk” Naomi E. Allen, MSc, DPhil, University of Oxford in Oxford, Journal of the National Cancer Institute, 2016;108:djw153
   https://www.renalandurologynews.com/home/news/urology/prostate-cancer/selenium-may-cut-aggressive-prostate-cancer-risk/
2. “Selenium for preventing cancer”, Vinceti M, Filippini T, Del Giovane C, Dennert G, Zwahlen M, Brinkman M, Zeegers MPA, Horneber M, D'Amico R, Crespi CM, 29 January 2018
   https://www.ncbi.nlm.nih.gov/pubmed/24683040

Saw Palmetto

1. Saw Palmetto for Prostate Disorders
   https://www.aafp.org/afp/2003/0315/p1281.html
2. Saw Palmetto for Benign Prostatic Hyperplasia
   https://www.nejm.org/doi/full/10.1056/NEJMoa053085

Plant Sterol Complex (Beta-sitosterol)

1. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review.
   https://www.ncbi.nlm.nih.gov/pubmed/10368239

Pygeum africanum

1. “Phytosterol Pygeum africanum regulates prostate cancer in vitro and in vivo” Shenouda, Nader & Sakla, Mary & Newton, Leslie & Besch-Williford, Cynthia & Greenberg, Norman & Macdonald, Ruth & Lubahn, Dennis. (2007). Endocrine. 31. 72-81. 10.1007/s12020-007-0014-y.
   https://link.springer.com/article/10.1007/s12020-007-0014-y
2. “Pygeum africanum for benign prostatic hyperplasia”. General Internal Medicine (111-0), Minneapolis VA/VISN 13 Center for Chronic Disease Outcomes Research
   https://www.ncbi.nlm.nih.gov/pubmed/11869585

Red Raspberry

1. “Protective Role of Dietary Berries in Cancer”, Aleksandra S. Kristo, Dorothy Klimis-Zacas, Angelos K. Sikalidis, Antioxidants (Basel) 2016 Dec; 5(4): 37. Published online 2016 Oct 19. doi: 10.3390/antiox5040037, PMCID: PMC5187535
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187535/
2. “Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro”, Center for Human Nutrition, David Geffen School of Medicine, University of California
   https://www.ncbi.nlm.nih.gov/pubmed/17147415
3. "Anticancer Effects of Red Raspberries on Immune Cells and Blood Parameters", Romero, Jannet, Clemson University (2011)
   https://pdfs.semanticscholar.org/4854/feabc973efb706dbde7bce51ab5640cc54e9.pdf

Graviola Leaf Powder

1. “Emerging therapeutic potential of graviola and its constituents in cancers”, Carcinogenesis, Volume 39, Issue 4, April 2018
   https://academic.oup.com/carcin/article/39/4/522/4859483
2. “Potential Benefits of Annona muricata in Combating Cancer: A Review”, School of Medical Sciences, Universiti Sains Malaysia, 2018 Feb 28
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862046/

Green Tea Leaf

1. “Green tea polyphenols for prostate cancer chemoprevention: A translational perspective”, J.J. Johnson, H.H. Bailey and H. Mukhtar, Phytomedicine. 2010 Jan
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789276/
2. “Chemopreventive Effects of Tea in Prostate Cancer: Green Tea vs. Black Tea”, Susanne M. Henning, Piwen Wang, and David Heber, Mol Nutr Food Res. 2011 Jun
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163457/

Cat's Claw Bark

1. Gonzales GF, Valerio LG. Medicinal plants from Peru: a review of plants as potential agents against cancer. Anticancer Agents Med Chem. 2006
   https://www.ncbi.nlm.nih.gov/pubmed/17017852
2. Sheng Y, et al. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa. Anticancer Res. 1998
   https://www.ncbi.nlm.nih.gov/pubmed/9858909

Broccoli Leaf

1. “Eat Your Broccoli: Study Finds Strong Anti-Cancer Properties In Cruciferous Veggies”, Oregon State University, ScienceDaily, 18 May 2007.
   https://www.sciencedaily.com/releases/2007/05/070517100315.htm
2. "Natural compound found in broccoli reawakens the function of potent tumor suppressor: Finding offers potential novel approach to cancer treatment and prevention." , Beth Israel Deaconess Medical Center, ScienceDaily, 16 May 2019
   https://www.sciencedaily.com/releases/2019/05/190516142913.htm

Tomato Fruit Powder

1. “Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies”, Chen J, Song Y, Zhang L., West China School of Public Health, Sichuan University
   https://www.ncbi.nlm.nih.gov/pubmed/23883692
2. Tomato lycopene and its role in human health and chronic disease., Agarwal S, Rao AV, CMAJ 2000;163(6):739–744
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC80172/

Stinging Nettle Leaf Powder

1. “Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia” Hirano, T., Homma, M., and Oka, K. Planta Med 1994;60(1):30-33
   https://www.ncbi.nlm.nih.gov/pubmed/7510891
2. “Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots”, Wagner H, Willer F, Samtleben R, and et al., Phytomedicine 1994, Mol Urol. 2000
   https://pubmed.ncbi.nlm.nih.gov/23195942/

Maitake Mushroom Powder

1. “Induction of apoptosis in human prostatic cancer cells with beta-glucan (Maitake mushroom polysaccharide)”, Department of Urology, New York Medical College, Valhalla, New York
   https://www.ncbi.nlm.nih.gov/pubmed/10851301
2. “Maitake D-fraction: healing and preventive potential for cancer”, H Namba - Journal of Orthomolecular Medicine, 1997
   http://orthomolecular.org/library/jom/1997/articles/1997-v12n01-p043.shtml

Reishi Mushroom

1. “Ganoderma lucidum (Reishi mushroom) for cancer treatment”, Cochrane Database Syst Rev. 2016 Apr
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353236/
2. “Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3”, Jiang J, Slivova V, Valachovicova T, Harvey K, Sliva D, Int J Oncol. 2004 May
   https://www.ncbi.nlm.nih.gov/pubmed/15067330

Shiitake Mushroom Powder

1. Del Buono A, Bonucci M, Pugliese S, D'Orta A, Fioranelli M. Polysaccharide from Lentinus edodes for integrative cancer treatment: immunomodulatory effects on lymphocyte population. World Cancer Res J. 2016;3(1):e652
   https://www.wcrj.net/article/652
2. Grotto D, Bueno DC, Ramos GK, da Costa SR, Spim SR, Gerenutti M. Assessment of the safety of the shiitake culinary-medicinal mushroom, Lentinus edodes (Agaricomycetes), in rats: biochemical, hematological, and antioxidative parameters. In J Med Mushrooms. 2016;18(10):861-70.
   https://www.ncbi.nlm.nih.gov/pubmed/27910754

Additional References

1. https://www.sciencedirect.com/science/article/pii/S0160412021001148
2. https://www.hsph.harvard.edu/news/features/harmful-chemicals-in-personal-care-products/
3. https://www.sciencedirect.com/science/article/pii/S0160412021001148
4. https://www.sciencedirect.com/science/article/pii/S1995764514602583?via%3Dihub
5. https://ncbi.nlm.nih.gov/pmc/articles/PMC4259190/